ATF4 polyclonal antibody
产品名称: ATF4 polyclonal antibody
英文名称: ATF4 polyclonal antibody
产品编号: PAB6080
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of ATF4.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human ATF4.
- Sequence:
- C-EEVRKARGKKRVP
- Host:
- Goat
- Theoretical MW (kDa):
- 38.6
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Isolation of cDNAs for DNA-binding proteins which specifically bind to a tax-responsive enhancer element in the long terminal repeat of human T-cell leukemia virus type I.
Tsujimoto A, Nyunoya H, Morita T, Sato T, Shimotohno K.J Virol. 1991 Mar;65(3):1420-6.
- Entrez GeneID:
- 468
- Protein Accession#:
- NP_001666
- Gene Name:
- ATF4
- Gene Alias:
- CREB-2,CREB2,TAXREB67,TXREB
- Gene Description:
- activating transcription factor 4 (tax-responsive enhancer element B67)
- Omim ID:
- 604064
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication. [provided by RefSeq
- Other Designations:
- activating transcription factor 4,cAMP response element-binding protein 2