IKBKB (phospho T199) polyclonal antibody-抗体-抗体-生物在线
亚诺法生技股份有限公司（Abnova)
IKBKB (phospho T199) polyclonal antibody

IKBKB (phospho T199) polyclonal antibody

商家询价

产品名称： IKBKB (phospho T199) polyclonal antibody

英文名称： IKBKB (phospho T199) polyclonal antibody

产品编号： PAB18519

产品价格： null

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)
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进入展台

  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of IKBKB.
  • Immunogen:
  • Synthetic phosphopeptide corresponding to residues surrounding T199 of human IKBKB.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody is specific to IKBKB only when phosphorylated at T199.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Concentration:
  • 1 mg/mL
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (0.02% sodium azide, 50% glycerol).
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Recommend Usage:
  • Immunofluorescence (1:100-1:200)
    The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining of methanol-fixed HeLa cells using IKBKB (phospho T199) polyclonal antibody (Cat # PAB18519) (Red).
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 3551
  • Gene Name:
  • IKBKB
  • Gene Alias:
  • FLJ40509,IKK-beta,IKK2,IKKB,MGC131801,NFKBIKB
  • Gene Description:
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • Gene Summary:
  • NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM
  • Other Designations:
  • inhibitor of nuclear factor kappa B kinase beta subunit,nuclear factor NF-kappa-B inhibitor kinase beta
  • Interactome

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